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Senior Engineer II / Scientist II, Pilot Scale Development

Company: Biogen
Location: Bennett
Posted on: May 3, 2021

Job Description:

Job Description

About This Role

Biogen's Pilot Scale Development group will drive scale-up and development of early and late stage pipeline and partner programs. The core responsibilities include the ability to manage their work efficiently, maintain operational excellence, to meet project timelines and to influence other stakeholders across the development organization.

What You'll Do

  • Design laboratory experiments with minimal guidance and participate within larger team on execution
  • Perform independent data analysis and interpretation; develop strategies for optimization and troubleshooting
  • Mentor junior staff on mechanistic understanding of new process technologies and methodologies
  • Participate in external collaborations and consortiums to advance scientific understanding and further technology development
  • Provide technical expertise to team and peers across the organization in a collaborative manner to advance the overall pipeline beyond the programs directly responsible.

Who You Are

You will lead process development through deep understanding of process scalability, modeling, advanced process control, and drive new technology investment projects into cell culture manufacturing processes for manufacturing recombinant proteins at the pilot scale (50-1000L). Work will be centered around fed batch and continuous manufacturing platform development using stainless and disposable equipment.


Required Skills
  • Ph.D. in Biochemistry or Chemical Engineering with 2+ years of hands-on experience in process development
  • Master's degree Biochemistry or Engineering with 5+ years commensurate experience
  • Support manufacturing transfers and collaboratively troubleshoot in conjunction with the Manufacturing Sciences Organization
  • Document development work in concise reports and provide project updates in written and oral presentations including opportunities to present externally at industry forums and conferences
  • Support maintenance tasks and new technology evaluations for laboratory instrumentation; interact with outside vendors / suppliers
  • Bring experience and expertise in one or more of the following areas: continuous manufacturing, new technology development, advanced process control (APC), modeling, process scale-up
  • Technical resource for their team and others across the organization, thus in-depth knowledge of process scale-up, cell culture and its connectivity to downstream is important. The candidate will also play a significant role in the assessment and development of new innovative technologies and enhance fundamental understanding that will be crucial for successful next generation processes and technology platforms

Additional Information

Our mission to find therapies for neurological and rare diseases is a unique focus within our industry and this shared purpose is what connects us as a team. We work together to overcome obstacles and to follow the science. We are resilient as we strive to make an impact on our patients' lives and on changing the course of medicine. Together, we pioneer. Together, we thrive.

Keywords: Biogen, High Point , Senior Engineer II / Scientist II, Pilot Scale Development, Other , Bennett, North Carolina

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